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Cancer
Genetic Markers of Susceptibility Project
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The Cancer Genetic Markers of Susceptibility (CGEMS) is a three-year,
$14 million initiative that will identify genetic alterations that make people susceptible
to prostate and breast cancer. Scientists involved will use DNA available from five
large studies of prostate cancer and five large studies of breast cancer to “scan”
the genome for common genetic variations between patients who have these cancers
and controls who do not have cancer.
Learn more >>
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Background
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To help eliminate suffering and death due to cancer, the National Cancer Institute
is capitalizing on the momentum generated by advances in human genetic research.
The tools and information coming out of the Human Genome Project and the International
HapMap Project facilitate the investigation of the genetic contribution to different
types of cancer. This NCI Strategic Initiative will be coordinated through the Division
of Cancer Epidemiology and Genetics (DCEG), the NCI Core Genotyping Facility (CGF),
and the NCI Office of Cancer Genomics (OCG).
Learn more
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Spotlight
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Researchers Identify Genetic Variations That May Increase Breast Cancer Risk
March 29, 2009
Study identifies new genetic variations that may be associated with risk of sporadic breast cancer and confirms some previously identified associations between specific regions in the genome and breast cancer risk.
Press Release
View advance online publication released March 29, 2009 in Nature Genetics.
Data Portal Update
August 26, 2008
The summary CGEMS GWAS results are temporarily unavailable for public posting.
Individual level data are still available to investigators from certified scientific
institutions after approval of their submitted Data Access Request. Click Here for CGEMS Data Access Request instructions.
Multiple Loci Identified in Prostate Cancer Study
February 10, 2008
Study Looks at Multiple Loci and the Susceptibility to Prostate Cancer. More
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