Related Links
cancer Biomedical Informatics Grid™ (caBIG™)
The cancer Biomedical Informatics Grid™, or caBIG™, is a voluntary network or grid connecting individuals and institutions to enable the sharing of data and tools, creating a World Wide Web of cancer research. The goal is to speed the delivery of innovative approaches for the prevention and treatment of cancer. The infrastructure and tools created by caBIG also have broad utility outside the cancer community. caBIG is being developed under the leadership of the National Cancer Institute's Center for Bioinformatics.
To learn more about caBIG, visit https://cabig.nci.nih.gov.
Cancer Genome Anatomy Project (CGAP)
The goal of the NCI's Cancer Genome Anatomy Project is to determine the gene expression profiles of normal, precancer, and cancer cells, leading eventually to improved detection, diagnosis, and treatment for the patient. By collaborating with scientists worldwide, CGAP seeks to increase its scientific expertise and expand its databases for the benefit of all cancer researchers.
To learn more about CGAP, visit http://cgap.nci.nih.gov.
Cancer Genome Anatomy Project SNP500Cancer Database
The goal of the SNP500Cancer project is to resequence 102 reference samples to find known or newly discovered single nucleotide polymorphisms (SNPs) which are of immediate importance to molecular epidemiology studies in cancer. SNP500Cancer provides a central resource for sequence verification of SNPs.
To learn more about the Cancer Genome Anatomy Project SNP500Cancer Database, visit http://snp500cancer.nci.nih.gov.
Core Genotyping Facility (CGF)
The goal of the Core Genotyping Facility is to meet the genotyping and DNA sequencing needs of the NCI's Division of Cancer Epidemiology and Genetics (DCEG) and Center for Cancer Research (CCR). The facility performs high-throughput genotyping and sequencing to support genetic analysis for a broad range of projects for the intramural research program of the NCI.
To learn more about CGF, visit http://cgf.nci.nih.gov/.
Division of Cancer Epidemiology and Genetics (DCEG)
The Division of Cancer Epidemiology and Genetics (DCEG) is an intramural research program of the National Cancer Institute, National Institutes of Health, that conducts population and multidisciplinary research to discover the genetic and environmental determinants of cancer and new approaches to cancer prevention.
To learn more about DCEG, visit http://dceg.cancer.gov.
International HapMap Project
The goal of the International HapMap Project was to develop a haplotype map of the human genome. Often referred to as the HapMap, it describes the common patterns of human genetic variation.
The HapMap provides a key resource for researchers to use to find genes affecting health, disease and responses to drugs and environmental factors. The information produced by the project is now freely available in public databases to researchers around the world.
To learn more about the International HapMap Project, visit http://www.hapmap.org/.
Office of Cancer Genomics (OCG)
The mandate of Office of Cancer Genomics (OCG) at the National Cancer Institute is to enhance understanding of the molecular mechanisms of cancer, with the ultimate goal of improving the prevention, early detection, diagnosis, and treatment of cancer.
To learn more about OCG, visit http://www3.cancer.gov/ocg.
Prostate, Lung, Colorectal & Ovarian Cancer Screening Trial (PLCO)
The Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, or PLCO, is a large-scale clinical trial to determine whether certain cancer screening tests reduce deaths from prostate, lung, colorectal and ovarian cancer. Together, these four cancers account for 42 percent of all diagnosed cancers in the United States. Sponsored and run by the NCI’s Division of Cancer Prevention, in collaboration with the Division of Cancer Epidemiology and Genetics, the PLCO trial is taking place at 10 Screening Centers across the country.
To learn more about PLCO, visit http://plco.cancer.gov
The Cancer Genome Atlas (TCGA)
The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing. TCGA is a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI), which are both part of the National Institutes of Health, U.S. Department of Health and Human Services.
To learn more about TCGA, visit http://cancergenome.nih.gov.
The Nurses’ Health Study
The Nurses' Health Study, established in 1976 by Dr. Frank Speizer, and the Nurses' Health Study II, established in 1989 by Dr. Walter Willett, are among the largest prospective investigations into the risk factors for major chronic diseases in women. The studies have grown to include a team of clinicians, epidemiologists, and statisticians at the Channing Laboratory along with collaborating investigators and consultants in the surrounding medical community of the Harvard Medical School, Harvard School of Public Health, Brigham and Women's Hospital, Dana Farber Cancer Institute, Boston Children's Hospital, and Beth Israel Deaconess Medical Center.
To learn more about the Nurses’ Health Study, visit http://www.channing.harvard.edu/nhs.
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